Adipokines and Systemic Rheumatic Diseases: Linking Inflammation, Immunity and Metabolism
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منابع مشابه
Adiponectin: An Attractive Marker for Metabolic Disorders in Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory lung disease which may be complicated by development of co-morbidities including metabolic disorders. Metabolic disorders commonly associated with this disease contribute to lung function impairment and mortality. Systemic inflammation appears to be a major factor linking COPD to metabolic alterations. Adipose tissue seems t...
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The metabolic syndrome (MetS) is a cluster of cardiometabolic disorders that result from the increasing prevalence of obesity. The major components of MetS include insulin resistance, central obesity, dyslipidemia, and hypertension. MetS identifies the central obesity with increased risk for cardiovascular diseases (CVDs) and type-2 diabetes mellitus (T2DM). Patients with rheumatic diseases, su...
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Introduction: Several parameters including induced inflammation by immune system, overgrowth of adipose tissue, and hypertrophied adipocytes lead to dyslipidemia, imbalanced proinflammatory, and antiinflammatory adipokines secretion. According to the adipokines expression in various pathological conditions like obesity, diabetes, atherosclerosis and inflammatory diseases, adipokines as biomarke...
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Patients with rheumatic diseases have an increased risk of mortality by cardiovascular events. In fact, several rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, and ankylosing spondylitis are associated with a higher prevalence of cardiovascular diseases (CVDs). Although traditional cardiovascular risk factors have been involved in the pathogenesis ...
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Pregnancy could be a challenge for physicians managing women with rheumatic diseases. Many of these diseases affect women of child-bearing age. Awareness of safe drugs, pregnancy effects on disease, and the effect of pregnancy are vitally important. For better results a group consisted of a gynecologist and internal physician should work together to these women. In general, active inflammation ...
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